To be eligible for the B.Com degree program at Radhanagari Mahavidyalaya, Kolhapur, candidates must have completed their 10+2 education from a recognized board with a minimum aggregate of 50%. Additionally, candidates must have studied Commerce as a subject in their 10+2 education. The selection process may also include a written entrance exam or an interview. It is important for candidates to have a strong foundation in accounting, economics, and business studies to excel in the B.Com program at Radhanagari Mahavidyalaya.